Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
نویسندگان
چکیده
منابع مشابه
Synthesis of new potentially bioactive bicyclic 2-pyridones.
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are reported. These reactions afforded the target bicyclic 2-pyridones in good to excellent yields.
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Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
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ژورنال
عنوان ژورنال: Molecules
سال: 2005
ISSN: 1420-3049
DOI: 10.3390/10101318